The following information will help parents, caregivers, educators and professionals learn about KCNA2 epilepsy, diagnosis, treatment, and how educators can accommodate students dealing with KCNA2 challenges. You can get to know and learn from families from around the world by reading their stories and answers to frequently asked questions.
What is KCNA2 Epilepsy?
KCNA2 epileptic encephalopathy is a seizure disorder caused by a mutation (or error) on the KCNA2 potassium channel. The mutation in the KCNA2 gene causes the potassium channel to function improperly. Depending on the mutation, the KCNA2 channel may be hyperexcitable (gain of function), electrically silenced (loss of function), or have a combination of both excitability (gain) and silence (loss) of function. All three types cause various types of seizures and other neurological challenges.
Treatment for KCNA2 Epilepsy
Clinical assessments such as EEG’s and MRI’s will inform you about the type of seizure activity one is experiencing. Genetic testing will clarify the type of mutation found in the KCNA2 gene. Treatment most likely will involve a trial of medications to control seizures. Various types of therapies may be helpful such as (but not limited to) physical, occupational, speech, music, and movement to help your child develop life skills and self-help skills. Therapy can also promote motor development, coordination, strength, and balance.
Therapy & Education
Students with KCNA2 can learn and succeed in school, just like their peers. However, they may need academic accommodations to help them manage the constant interruptions they have in concentration and learning due to seizures. They may also have to contend with the side effects of medications. Educators and parents work together to identify academic accommodations that are appropriate for each student, making it possible to create the optimal learning environment.
Our Stories: Around the Globe
Families from around the world who are affected by KCNA2 have searched ideas, treatment interventions, and research opportunities to help with the challenges of KCNA2. Collectively, we share our stories from around the world.