Real Stories. Real Science. Real Hope.

This figure shows how KCNA2 mutations change brain activity. Gain-of-Function (top, yellow) makes neurons overactive and fire too much, too soon. Loss-of-Function (bottom, purple) weakens the brain’s braking system and can’t stop signals properly. Both disrupt balance and can lead to seizures.

Understanding A Gain-of-Function (GoF) KCNA2 Diagnosis

When someone you love is diagnosed with KCNA2, one of the first things you may hear is that the variation […]

Understanding A Loss-of-Function (LoF) KCNA2 Diagnosis

When someone you care about receives a KCNA2 diagnosis, a lot of questions can follow and one of the first […]

Understanding A Combination Gain-and-Loss-of-Function (MoF) KCNA2 Diagnosis

When a potassium channel doesn’t know which signal to follow, the result can be unpredictable. Some parts open too easily. […]

little kid with cerebral palsy has musculoskeletal therapy by doing exercises in body fixing

Understanding The Connections Between Epilepsy & Sleep

Sleep is supposed to be the time when everything quiets down. The body rests, the brain resets, and we wake […]

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KCNA2 Epilepsy Newsletter

A Note from Nancy I’m excited to tell you that our KCNA2 organization will donate $25,000 to KCNA2 research this […]

KCNA2 Epilepsy – Newsletter February 2023

A Note from Nancy I’m excited to announce that our group has made its presence known around the world. We […]

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KCNA2 – Medical Update – February 2023

A Note from Nancy We provide this newsletter to researchers, neurologists and treatment teams to stay informed about KCNA2 research. […]

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KCNA2 Epilipsy Newsletter September 2022

A Note from Nancy Since the first KCNA2 Newsletter was published in January, 2022, our group has engaged in several […]

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KCNA2 Epilipsy Newsletter – January 2022

A Note from Nancy I am continually inspired by our growing “KCNA2 family” who initially connected in 2017 through Facebook. […]

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